Prophetic chain-smoking bisexual, Mantis, finds herself in the midst of a nightmarish demon apocalypse and soon seeks help from her estranged friend, Black Eyed Betty, a born-again former prostitute. It isn’t until Betty’s seven-year-old son, Gabriel, is abducted, that they decide
to join forces on a dark journey to rescue him.

Hours later, a bubbly exotic dancer and her smitten co-worker are recruited to aid them on their hilariously hellish misadventure. With Mantis at the helm, the band of unlikely misfit degenerates sets out on a bizarre thrill-ride through the quirky American South,
battling sinister creatures, chasing painful memories, and negotiating with a slew of twisted
characters for pieces of a mysterious holy relic.